The ageing pancreas
Brown, James E. (2012). The ageing pancreas. British journal of diabetes and vascular disease, 12 (3), pp. 141-145.
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Official URL: http://dvd.sagepub.com/content/12/3/141
Type 2 diabetes is historically associated with older adults, and glucose tolerance is known to decline with advancing age. During the course of natural ageing, changes in many peripheral tissues contribute to this deterioration of glucose homeostasis. Included in this process are changes to the structure and function of the pancreatic islets, which undergo deviation in endocrine responses to glycaemic challenge. Current knowledge about the changes seen in the ageing pancreas is reviewed here.
|Additional Information:||Copyright 2012 Elsevier B.V., All rights reserved.|
|Uncontrolled Keywords:||ageing, pancreatic islets , β-cells|
|Divisions:||Schools_of_Study > Life & Health Sciences > Biosciences (LHS)|
|Deposited By:||Prof Alfred Admin|
|Deposited On:||04 Dec 2012 11:24|
|Last Modified:||08 Jan 2013 18:09|
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